Faddtm2Wnt
Targeted Allele Detail
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Symbol: |
Faddtm2Wnt |
Name: |
Fas associated via death domain; targeted mutation 2, Astar Winoto |
MGI ID: |
MGI:4837701 |
Synonyms: |
FADDfloxneo |
Gene: |
Fadd Location: Chr7:144132060-144136178 bp, - strand Genetic Position: Chr7, 88.85 cM
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Alliance: |
Faddtm2Wnt page
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Mouse Generated: |
Earliest citation of chimera generation:
J:162312
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: The knockout construct contains a loxP flanked neomycin resistance cassette inserted between exons 1 and 2 of FADD, and an additional loxP site upstream of exon 1.
(J:162312)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Fadd Mutation: |
18 strains or lines available
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Original: |
J:162312 Osborn SL, et al., Fas-associated death domain (FADD) is a negative regulator of T-cell receptor-mediated necroptosis. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13034-9 |
All: |
1 reference(s) |
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