Tg(Dach1-Pax6)1Jlr
Transgene Detail

Summary

• Symbol: Tg(Dach1-Pax6)1Jlr
• Name: transgene insertion 1, John Rubenstein
• MGI ID: MGI:4837141
• Synonyms: D6-Pax6, Tg(Dach1-Pax6)#Fjl
• Transgene: Tg(Dach1-Pax6)1Jlr Location: unknown
• Alliance: Tg(Dach1-Pax6)1Jlr page

Transgene origin

• Strain of Origin: (C57BL/6 x BALB/c)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Dach1-Pax6)1Jlr expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Pax6 (MGI:97490)

• Mutation details: A 5.7 kb fragment containing the Dach1 promoter was used to drive expression of Pax6 in the ventricular zone and cortical plate of the brain. (J:149737)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:149737 Sansom SN, et al., The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009 Jun;5(6):e1000511
• All: 1 reference(s)