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Mdm2tm1.1Ypz
Targeted Allele Detail
Nomenclature
Symbol: Mdm2tm1.1Ypz
Name: transformed mouse 3T3 cell double minute 2; targeted mutation 1.1, Yangping Zhang
MGI ID: MGI:4836988
Synonyms: Mdm2C305F
Gene: Mdm2  Location: Chr10:117688888-117710758 bp, - strand  Genetic Position: Chr10, 66.32 cM, cytoband C1-C3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:164200
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (knock-in)
Mutations:    Insertion, Nucleotide substitutions
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mdm2 Mutation:  29 strains or lines available
References
Original:  J:164200 Macias E, et al., An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction. Cancer Cell. 2010 Sep 14;18(3):231-43
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory