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Cep290tm1.1Jgg
Targeted Allele Detail
Nomenclature
Symbol: Cep290tm1.1Jgg
Name: centrosomal protein 290; targeted mutation 1.1, Joseph Gleeson
MGI ID: MGI:4835226
Gene: Cep290  Location: Chr10:100488289-100573655 bp, + strand  Genetic Position: Chr10, 51.48 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 36, 37 and the intervening intronic sequence were replaced by a targeting cassette containing "loxP-exon36-intron-exon37-loxP-neomycin resistance-loxP". The floxed sequences were deleted by crossing mice with Tg(EIIa-cre)C5379Lmgd mice on an ICR genetic background. Deletion of exons 36 and 37 creates a premature stop codon. (J:101977)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cep290 Mutation:  57 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2016;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory