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Cep290tm1Jgg
Targeted Allele Detail
Summary
Symbol: Cep290tm1Jgg
Name: centrosomal protein 290; targeted mutation 1, Joseph Gleeson
MGI ID: MGI:4835225
Synonyms: Cep290fl, Cep290 floxed
Gene: Cep290  Location: Chr10:100323410-100409527 bp, + strand  Genetic Position: Chr10, 51.48 cM
Alliance: Cep290tm1Jgg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:172420
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsExons 36, 37 and the intervening intronic sequence were replaced by a targeting cassette containing "loxP-exon36-intron-exon37-loxP-neomycin resistance-loxP". (J:172420)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cep290 Mutation:  126 strains or lines available
References
Original:  J:172420 Lancaster MA, et al., Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome. Nat Med. 2011 Jun;17(6):726-31
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory