Tg(Msx2-cre/ERT)27Alj
Transgene Detail
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Symbol: |
Tg(Msx2-cre/ERT)27Alj |
Name: |
transgene insertion 27, Alexandra L Joyner |
MGI ID: |
MGI:4834769 |
Synonyms: |
Msx2-CreERT |
Transgene: |
Tg(Msx2-cre/ERT)27Alj Location: unknown
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Alliance: |
Tg(Msx2-cre/ERT)27Alj page
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Msx2-cre/ERT)27Alj expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
Not Specified |
Msx2 |
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Mutation details: A transgenic construct was generated that contained cre/ERT, beta-globin intron, LacZtag, and SV40polyA coding sequences under control of an apical ectodermal ridge (AER)-specific 520 bp Msx2 promoter. The purified construct was injected into Swiss Webster zygotes. Nine founders were generated with eight transmitting the transgene. Four expressed cre/ERT in the apical ectodermal ridge (AER). Studies were performed using one line (no. 27) that showed the strongest expression.
(J:62572)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Msx2
(species not specified)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:62572 Kimmel RA, et al., Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation. Genes Dev. 2000 Jun 1;14(11):1377-89 |
All: |
1 reference(s) |
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