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Tg(Msx2-cre/ERT)27Alj
Transgene Detail
Nomenclature
Symbol: Tg(Msx2-cre/ERT)27Alj
Name: transgene insertion 27, Alexandra L Joyner
MGI ID: MGI:4834769
Synonyms: Msx2-CreERT
Transgene: Tg(Msx2-cre/ERT)27Alj  Location: unknown  
Transgene
origin
Strain of Origin:  Swiss Webster
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mutation detailsA transgenic construct was generated that contained cre/ERT, beta-globin intron, LacZtag, and SV40polyA coding sequences under control of an apical ectodermal ridge (AER)-specific 520 bp Msx2 promoter. The purified construct was injected into Swiss Webster zygotes. Nine founders were generated with eight transmitting the transgene. Four expressed cre/ERT in the apical ectodermal ridge (AER). Studies were performed using one line (no. 27) that showed the strongest expression. (J:62572)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Msx2     Summary of all recombinase alleles driven by Msx2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:62572 Kimmel RA, et al., Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation. Genes Dev. 2000 Jun 1;14(11):1377-89
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/15/2020
MGI 6.15
The Jackson Laboratory