Dclre1b^tm1.1Tdl
Targeted Allele Detail

Summary

• Symbol: Dclre1b^tm1.1Tdl
• Name: DNA cross-link repair 1B; targeted mutation 1.1, Titia de Lange
• MGI ID: MGI:4830567
• Synonyms: Apollo^F
• Gene: Dclre1b Location: Chr3:103707921-103716703 bp, - strand Genetic Position: Chr3, 45.52 cM
• Alliance: Dclre1b^tm1.1Tdl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163935
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette with a 3' loxP site was inserted downstream of exon 3. Flp mediated recombination removed the neo cassette leaving exons 2 and 3 floxed. (J:163935)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dclre1b Mutation: 20 strains or lines available

References

• Original: J:163935 Wu P, et al., Apollo contributes to G overhang maintenance and protects leading-end telomeres. Mol Cell. 2010 Aug 27;39(4):606-17
• All: 1 reference(s)