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Cecr2tm1.1Hemc
Targeted Allele Detail
Nomenclature
Symbol: Cecr2tm1.1Hemc
Name: CECR2, histone acetyl-lysine reader; targeted mutation 1.1, Heather E McDermid
MGI ID: MGI:4829945
Gene: Cecr2  Location: Chr6:120643330-120748151 bp, + strand  Genetic Position: Chr6, 56.97 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:163648
Parent Cell Line:  iTL BA1 (ES Cell)
Strain of Origin:  (C57BL/6NTac x 129S6/SvEvTac)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon 1 was floxed by homologous recombination. The exon was removed by cre mediate recombination. (J:163648)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 5 assay results
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cecr2 Mutation:  71 strains or lines available
References
Original:  J:163648 Fairbridge NA, et al., Cecr2 mutations causing exencephaly trigger misregulation of mesenchymal/ectodermal transcription factors. Birth Defects Res A Clin Mol Teratol. 2010 Aug;88(8):619-25
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory