Prdx1^tm1Brs
Targeted Allele Detail

Summary

• Symbol: Prdx1^tm1Brs
• Name: peroxiredoxin 1; targeted mutation 1, Brian Seed
• MGI ID: MGI:4829866
• Gene: Prdx1 Location: Chr4:116542796-116557196 bp, + strand Genetic Position: Chr4, 53.28 cM
• Alliance: Prdx1^tm1Brs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163809
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The locus was interrupted by the insertion of a FRT flanked neo cassette within an intact bacterial artificial chromosome. Correctly integrated clones were identified by a simple screening procedure based on chromosomal fluorescence in situ hybridization (FISH). (J:163809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prdx1 Mutation: 37 strains or lines available

References

• Original: J:163809 Yang Y, et al., Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes. Nat Biotechnol. 2003 Apr;21(4):447-51
• All: 2 reference(s)