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Dll1m1Mhda
Chemically induced Allele Detail
Summary
Symbol: Dll1m1Mhda
Name: delta like canonical Notch ligand 1; mutation 1, Martin Hrabe de Angelis
MGI ID: MGI:4821259
Synonyms: Dll1C413Y
Gene: Dll1  Location: Chr17:15587616-15597134 bp, - strand  Genetic Position: Chr17, 8.95 cM
Alliance: Dll1m1Mhda page
Mutation
origin
Strain of Origin:  C3HeB/FeJ
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsENU mutagenesis induced a missense mutation in exon 8 that results in the amino acid substitution of tyrosine for cysteine at position 413. (J:150183)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dll1 Mutation:  46 strains or lines available
References
Original:  J:150183 Rubio-Aliaga I, et al., Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes. PLoS One. 2009;4(6):e6054
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory