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Tg(ACTB-UPF1*R844C)581Hcd
Transgene Detail
Nomenclature
Symbol: Tg(ACTB-UPF1*R844C)581Hcd
Name: transgene insertion 581, Harry C Dietz
MGI ID: MGI:4820740
Synonyms: RNT1 Dom Neg
Transgene: Tg(ACTB-UPF1*R844C)581Hcd  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x 129)F1
Transgene
description
Transgene Type:    Transgenic (Dominant negative, Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(ACTB-UPF1*R844C)581Hcd expresses 1 gene
 
Mutation detailsThe human beta actin (ACTB) promoter drives expression of a dominant negative R844C mutant cDNA of the human UPF1 regulator of nonsense transcripts homolog (yeast) (UPF1) gene. Line 581 was generated. (J:162990)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:162990 Dietz HC, JR strain 10939. MGI Direct Data Submission. 2010;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory