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Tg(Tek-B4galnt2)1108Dgi
Transgene Detail
Nomenclature
Symbol: Tg(Tek-B4galnt2)1108Dgi
Name: transgene insertion 1108, David Ginsburg
MGI ID: MGI:4819742
Synonyms: Tie2-B4galnt2
Transgene: Tg(Tek-B4galnt2)1108Dgi  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6J x SJL)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Tek-B4galnt2)1108Dgi expresses 1 gene
 
Mutation detailsA transgenic vector was generated to include the endothelial-specific receptor tyrosine kinase (Tek) driving vascular endothelial specific expression of beta-1,4-N-acetyl-galactosaminyl transferase 2 (B4galnt2), followed by a simian virus 40 intron and a polyadenylation signal (polyA). This transgene is lacking 23 bp of B4galnt2 3'UTR for detection purposes. Line 1108 was established. (J:52069)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:52069 Mohlke KL, et al., Mvwf, a dominant modifier of murine von Willebrand factor, results from altered lineage-specific expression of a glycosyltransferase. Cell. 1999 Jan 8;96(1):111-20
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory