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Tg(Myh6-TNNT2*R141W)#Ajm
Transgene Detail
Nomenclature
Symbol: Tg(Myh6-TNNT2*R141W)#Ajm
Name: transgene insertion, Ali J Marian
MGI ID: MGI:4819721
Synonyms: cTnT-W141
Transgene: Tg(Myh6-TNNT2*R141W)#Ajm  Location: unknown  
Transgene
origin
Strain of Origin:  C3H and C57BL/6 and ICR
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Myh6-TNNT2*R141W)#Ajm expresses 1 gene
 
Mutation detailsThis transgene consists of a 5.5 Kb fragment of the murine Myh6 promoter driving expression of a full length human TNNT2 cDNA containing a substitution that results in an Arg 141 Trp mutation. (J:161899)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:161899 Lombardi R, et al., Differential interactions of thin filament proteins in two cardiac troponin T mouse models of hypertrophic and dilated cardiomyopathies. Cardiovasc Res. 2008 Jul 1;79(1):109-17
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory