Vangl2^tm1.1Yy
Targeted Allele Detail

Summary

• Symbol: Vangl2^tm1.1Yy
• Name: VANGL planar cell polarity 2; targeted mutation 1.1, Yingzi Yang
• MGI ID: MGI:4819588
• Synonyms: Vangl2^f
• Gene: Vangl2 Location: Chr1:171828527-171856011 bp, - strand Genetic Position: Chr1, 79.54 cM
• Alliance: Vangl2^tm1.1Yy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:162640
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 4 and an FRT flanked neo cassette with a 3' loxP site was inserted downstream of exon 5. Flp mediated recombination removed the neo cassette leaving exons 4 and 5 floxed. (J:162640)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vangl2 Mutation: 34 strains or lines available

References

• Original: J:162640 Song H, et al., Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning. Nature. 2010 Jul 15;466(7304):378-82
• All: 10 reference(s)