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Eef2ktm1Agry
Targeted Allele Detail
Nomenclature
Symbol: Eef2ktm1Agry
Name: eukaryotic elongation factor-2 kinase; targeted mutation 1, Alexey G Ryazanov
MGI ID: MGI:4819586
Gene: Eef2k  Location: Chr7:120842831-120907450 bp, + strand  Genetic Position: Chr7, 64.95 cM, cytoband F3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:162129
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 7 and most of exon 8 were replaced with a neo cassette via homologous recombination. Western blot analysis confirmed the absence of protein expression in homozygous mice. (J:208406)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Eef2k Mutation:  18 strains or lines available
References
Original:  J:162129 Khan AA, et al., Resveratrol regulates pathologic angiogenesis by a eukaryotic elongation factor-2 kinase-regulated pathway. Am J Pathol. 2010 Jul;177(1):481-92
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory