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Targeted Allele Detail
Symbol: Slc6a9tm1.1Veul
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 9; targeted mutation 1.1, Volker Eulenburg
MGI ID: MGI:4818449
Synonyms: GlyT-
Gene: Slc6a9  Location: Chr4:117834506-117875198 bp, + strand  Genetic Position: Chr4, 53.62 cM
Germline Transmission:  Earliest citation of germline transmission: J:161993
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA floxed neomycin selection cassette was inserted in intron 2 and a third loxP was inserted in intron 4. The neomycin selection cassette was then removed by transient cre expression leaving exons 3 and 4 floxed. Subsequently, mice were crossed to Tg(EIIa-cre)C5379Lmgd mice to excise exons 3 and 4 creating a knockout allele. (J:161993)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc6a9 Mutation:  11 strains or lines available
Original:  J:161993 Eulenburg V, et al., Glial glycine transporter 1 function is essential for early postnatal survival but dispensable in adult mice. Glia. 2010 Jul;58(9):1066-73
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory