Tnr^tm2Msch
Targeted Allele Detail

Summary

• Symbol: Tnr^tm2Msch
• Name: tenascin R; targeted mutation 2, Melitta Schachner
• MGI ID: MGI:4818357
• Synonyms: Tnr^flox
• Gene: Tnr Location: Chr1:159351339-159759299 bp, + strand Genetic Position: Chr1, 69.03 cM, cytoband E2
• Alliance: Tnr^tm2Msch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:162048
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: One loxP site was inserted upstream of exon 3 and a neomycin selection cassette flanked by tandemly arranged loxP and FRT sites was placed downstream. Transient cre expression was then used to create ES cells in which exon 3 was floxed. (J:162048)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnr Mutation: 67 strains or lines available

References

• Original: J:162048 Meier ID, et al., Short DNA sequences inserted for gene targeting can accidentally interfere with off-target gene expression. FASEB J. 2010 Jun;24(6):1714-24
• All: 1 reference(s)