Tg(ED-L2-cre)267Jkat
Transgene Detail

Summary

• Symbol: Tg(ED-L2-cre)267Jkat
• Name: transgene insertion 267, Jonathan P Katz
• MGI ID: MGI:4462391
• Synonyms: ED-L2/Cre, L2cre, Tg(ED-L2-cre)#Jkat
• Transgene: Tg(ED-L2-cre)267Jkat Location: unknown
• Alliance: Tg(ED-L2-cre)267Jkat page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(ED-L2-cre)267Jkat expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  virus	ED-L2

• Mutation details: Expression of cre recombinase is driven by a 782 bp fragment of the Epstein-Barr virus (EBV) ED-L2 promoter. Transgenic founders were crossed to R26R reporter mice and lacZ staining was observed throughout the esophageal epithelia. (J:161868)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	ED-L2 (virus) Summary of all recombinase alleles driven by ED-L2.

Tumor Data

List all tumor models in MMHCdb carrying Tg(ED-L2-cre)267Jkat

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:161868 Tetreault MP, et al., Esophageal squamous cell dysplasia and delayed differentiation with deletion of kruppel-like factor 4 in murine esophagus. Gastroenterology. 2010 Jul;139(1):171-81.e9
• All: 13 reference(s)