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Targeted Allele Detail
Symbol: Ncoa3tm2.2Jxu
Name: nuclear receptor coactivator 3; targeted mutation 2.2, Jianming Xu
MGI ID: MGI:4462058
Synonyms: SRC-3d
Gene: Ncoa3  Location: Chr2:165992636-166073242 bp, + strand  Genetic Position: Chr2, 86.22 cM, cytoband H2-H4
Germline Transmission:  Earliest citation of germline transmission: J:161101
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 11-12 were floxed and a FLP flanked Neo cassette was inserted within intron 17. The selection cassette and exons 11-12 were removed by flp and cre mediated recombination respectively. (J:161101)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ncoa3 Mutation:  173 strains or lines available
Original:  J:161101 Liu Z, et al., Generation and validation of a mouse line with a floxed SRC-3/AIB1 allele for conditional knockout. Int J Biol Sci. 2008;4(4):202-7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory