About   Help   FAQ
Ncoa3tm2.2Jxu
Targeted Allele Detail
Nomenclature
Symbol: Ncoa3tm2.2Jxu
Name: nuclear receptor coactivator 3; targeted mutation 2.2, Jianming Xu
MGI ID: MGI:4462058
Synonyms: SRC-3d
Gene: Ncoa3  Location: Chr2:165992636-166071470 bp, + strand  Genetic Position: Chr2, 86.22 cM, cytoband H2-H4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:161101
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 11-12 were floxed and a FLP flanked Neo cassette was inserted within intron 17. The selection cassette and exons 11-12 were removed by flp and cre mediated recombination respectively. (J:161101)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ncoa3 Mutation:  230 strains or lines available
References
Original:  J:161101 Liu Z, et al., Generation and validation of a mouse line with a floxed SRC-3/AIB1 allele for conditional knockout. Int J Biol Sci. 2008;4(4):202-7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/11/2017
MGI 6.10
The Jackson Laboratory