Add3^tm2.1Llp
Targeted Allele Detail

Summary

• Symbol: Add3^tm2.1Llp
• Name: adducin 3; targeted mutation 2.1, Luanne Peters
• MGI ID: MGI:4462035
• Gene: Add3 Location: Chr19:53128874-53235518 bp, + strand Genetic Position: Chr19, 47.18 cM
• Alliance: Add3^tm2.1Llp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:266350
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: An EGFP-pA cassette was inserted into exon 2, the first coding exon, and an FRT-flanked neomycin selection cassette was inserted into the downstream intron, which was excised by breeding to a mouse with germline expression of FLP1 recombinase, resulting in a null allele with expressed reporter and no neomycin selection sequence. (J:266350)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Add3 Mutation: 43 strains or lines available

References

• Original: J:266350 Sahr KE, et al., Analysis of gamma-adducin Gene Expression using and EGFP knockin strategy in mice. Poster session presented at:The American Society for Cell Biology 48th Annual Mtg.; San Francisco. 2008 Dec 13-17
• All: 1 reference(s)