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Add3tm2.1Llp
Targeted Allele Detail
Nomenclature
Symbol: Add3tm2.1Llp
Name: adducin 3 (gamma); targeted mutation 2.1, Luanne Peters
MGI ID: MGI:4462035
Gene: Add3  Location: Chr19:53128874-53235757 bp, + strand  Genetic Position: Chr19, 47.18 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:266350
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsAn EGFP-pA cassette was inserted into exon 2, the first coding exon, and an FRT-flanked neomycin selection cassette was inserted into the downstream intron, which was excised by breeding to a mouse with germline expression of FLP1 recombinase, resulting in a null allele with expressed reporter and no neomycin selection sequence. (J:266350)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Add3 Mutation:  31 strains or lines available
References
Original:  J:266350 Sahr KE, et al., Analysis of gamma-adducin Gene Expression using and EGFP knockin strategy in mice. Poster session presented at:The American Society for Cell Biology 48th Annual Mtg.; San Francisco.. 2008 Dec 13-17;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory