Add3^tm1.1Llp
Targeted Allele Detail

Summary

• Symbol: Add3^tm1.1Llp
• Name: adducin 3; targeted mutation 1.1, Luanne Peters
• MGI ID: MGI:4462003
• Synonyms: g-add^deltaneo
• Gene: Add3 Location: Chr19:53128874-53235518 bp, + strand Genetic Position: Chr19, 47.18 cM
• Alliance: Add3^tm1.1Llp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161920
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The neomycin resistance cassette that is flanked by Frt sites was removed by mating with mice expressing FLP1 recombinase, resulting in an exon 2 loxP flanked allele lacking the neomycin resistance sequence. (J:161920)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Add3 Mutation: 42 strains or lines available

References

• Original: J:161920 Sahr KE, et al., Targeted deletion of the gamma-adducin gene (Add3) in mice reveals differences in alpha-adducin interactions in erythroid and nonerythroid cells. Am J Hematol. 2009 Jun;84(6):354-61
• All: 1 reference(s)