Esr1tm1.1Rake
Targeted Allele Detail
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Symbol: |
Esr1tm1.1Rake |
Name: |
estrogen receptor 1 (alpha); targeted mutation 1.1, Ruth A Keri |
MGI ID: |
MGI:4461460 |
Synonyms: |
Ex3alphaERKO |
Gene: |
Esr1 Location: Chr10:4561989-4955633 bp, + strand Genetic Position: Chr10, 2.03 cM
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Alliance: |
Esr1tm1.1Rake page
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Germline Transmission: |
Earliest citation of germline transmission:
J:161401
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Two loxP sites were inserted to flank Exon 3, the coding region for the DNA binding domain. Exon 3 was deleted by Cre-mediated recombination.
(J:161401)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Esr1 Mutation: |
67 strains or lines available
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Original: |
J:161401 Bernardo GM, et al., FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis. Development. 2010 Jun;137(12):2045-54 |
All: |
1 reference(s) |
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