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Fastktm1.1Andp
Targeted Allele Detail
Nomenclature
Symbol: Fastktm1.1Andp
Name: Fas-activated serine/threonine kinase; targeted mutation 1, Paul Anderson
MGI ID: MGI:4461026
Gene: Fastk  Location: Chr5:24646036-24650280 bp, - strand  Genetic Position: Chr5, 11.78 cM, cytoband A3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:160443
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe coding sequence was replaced by a floxed neo cassette. The selection cassette was removed by cre mediated recombination. (J:160443)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fastk Mutation:  17 strains or lines available
References
Original:  J:160443 Simarro M, et al., Fas-activated serine/threonine phosphoprotein promotes immune-mediated pulmonary inflammation. J Immunol. 2010 May 1;184(9):5325-32
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory