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Fgfr3tm6Cxd
Targeted Allele Detail
Nomenclature
Symbol: Fgfr3tm6Cxd
Name: fibroblast growth factor receptor 3; targeted mutation 6, Chu-Xia Deng
MGI ID: MGI:4459830
Synonyms: Fgfr3floxneo
Gene: Fgfr3  Location: Chr5:33721724-33737067 bp, + strand  Genetic Position: Chr5, 17.83 cM, cytoband B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:161199
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsExon 9 and 10 were floxed and a neo cassette followed by a loxP site were inserted within intron 10 by homologous recombination. RT-PCR showed that the allele is not transcribed. (J:161199)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgfr3 Mutation:  10 strains or lines available
References
Original:  J:161199 Su N, et al., Generation of Fgfr3 conditional knockout mice. Int J Biol Sci. 2010;6(4):327-32
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/17/2015
MGI 5.21
The Jackson Laboratory