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Clec4ntm1Yiw
Targeted Allele Detail
Nomenclature
Symbol: Clec4ntm1Yiw
Name: C-type lectin domain family 4, member n; targeted mutation 1, Yoichiro Iwakura
MGI ID: MGI:4459637
Synonyms: Dectin-2-
Gene: Clec4n  Location: Chr6:123229843-123247021 bp, + strand  Genetic Position: Chr6, 58.3 cM, cytoband F3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:160680
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 1 and 2 were replaced by a neomycin-resistance cassette. (J:160680)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Clec4n Mutation:  10 strains or lines available
References
Original:  J:160680 Saijo S, et al., Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans. Immunity. 2010 May 28;32(5):681-91
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory