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Targeted Allele Detail
Symbol: Timd4tm1Wouy
Name: T cell immunoglobulin and mucin domain containing 4; targeted mutation 1, Wenjun Ouyang
MGI ID: MGI:4459454
Synonyms: Tim-4-
Gene: Timd4  Location: Chr11:46810800-46844332 bp, + strand  Genetic Position: Chr11, 28.09 cM
Germline Transmission:  Earliest citation of germline transmission: J:160304
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 2 and 3 were replaced with a neo cassette. The absence of protein expression was confirmed by FACS analysis on cells from the peritoneal cavity. (J:160304)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Timd4 Mutation:  11 strains or lines available
Original:  J:160304 Wong K, et al., Phosphatidylserine receptor Tim-4 is essential for the maintenance of the homeostatic state of resident peritoneal macrophages. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8712-7
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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