Ffar3^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Ffar3^tm1Dgen
• Name: free fatty acid receptor 3; targeted mutation 1, Deltagen
• MGI ID: MGI:4459441
• Gene: Ffar3 Location: Chr7:30553755-30555603 bp, - strand Genetic Position: Chr7, 19.25 cM
• Alliance: Ffar3^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160365
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding region was replaced with a lacZ-neo cassette. Reduction in transcript expression was confirmed by quantitative RT-PCR in subcutaneous, retroperitoneal, omental, epididymal, mesentaeric, and interscapular brown adipose tissue. (J:160365)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ffar3 Mutation: 16 strains or lines available

References

• Original: J:160365 Zaibi MS, et al., Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids. FEBS Lett. 2010 Jun 3;584(11):2381-6
• All: 3 reference(s)