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Ffar3tm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: Ffar3tm1Dgen
Name: free fatty acid receptor 3; targeted mutation 1, Deltagen
MGI ID: MGI:4459441
Gene: Ffar3  Location: Chr7:30854330-30856178 bp, - strand  Genetic Position: Chr7, 19.25 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:160365
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe coding region was replaced with a lacZ-neo cassette. Reduction in transcript expression was confirmed by quantitative RT-PCR in subcutaneous, retroperitoneal, omental, epididymal, mesentaeric, and interscapular brown adipose tissue. (J:160365)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ffar3 Mutation:  6 strains or lines available
References
Original:  J:160365 Zaibi MS, et al., Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids. FEBS Lett. 2010 Jun 3;584(11):2381-6
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory