Col8a1tm1e(KOMP)Mbp
Targeted Allele Detail
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Symbol: |
Col8a1tm1e(KOMP)Mbp |
Name: |
collagen, type VIII, alpha 1; targeted mutation 1e, Mouse Biology Program, UC Davis |
MGI ID: |
MGI:4458459 |
Gene: |
Col8a1 Location: Chr16:57444621-57575100 bp, - strand Genetic Position: Chr16, 34.22 cM, cytoband C1.1
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Alliance: |
Col8a1tm1e(KOMP)Mbp page
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IMPC: |
Col8a1 gene page |
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Mutant Cell Lines: |
DEPD00519_3_A01, DEPD00519_3_A03, DEPD00519_3_A04, DEPD00519_3_B03, DEPD00519_3_B04, DEPD00519_3_D03, DEPD00519_3_E01, DEPD00519_3_E04, DEPD00519_3_G03, DEPD00519_3_G04 |
Germline Transmission: |
Earliest citation of germline transmission:
J:204812
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutation: |
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Insertion
Vector: L1L2_Bact_P
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Mutation details: The L1L2_Bact_P cassette was inserted at position 57449575 of Chromosome 16 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157064)
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Original: |
J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010; |
All: |
2 reference(s) |
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