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Targeted Allele Detail
Symbol: Mafatm1.1Rwst
Name: v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian); targeted mutation 1.1, Roland W Stein
MGI ID: MGI:4457890
Synonyms: MafAfl, MafA[lox/w]
Gene: Mafa  Location: Chr15:75617339-75620077 bp, - strand  Genetic Position: Chr15, 34.82 cM
Germline Transmission:  Earliest citation of germline transmission: J:94077
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA targeting vector was designed to place two loxP sites in tandem orientation to flank a 2355 bp fragment in the the region beginning 1106 bp upstream of the start codon, including 1081 bp of the coding sequence and ending 171 bp downstream of the stop codon. The vector also contained an FRT-flanked neomycin resistance cassette. The neo cassette was removed by crossing to Tg(ACTFLPe)9205Dym mice. (J:94077)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mafa Mutation:  16 strains or lines available
Original:  J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015;
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.21
The Jackson Laboratory