Mafa^tm1.1Rwst
Targeted Allele Detail

Summary

• Symbol: Mafa^tm1.1Rwst
• Name: MAF bZIP transcription factor A; targeted mutation 1.1, Roland W Stein
• MGI ID: MGI:4457890
• Synonyms: MafA^fl, MafA[lox/w]
• Gene: Mafa Location: Chr15:75617339-75620077 bp, - strand Genetic Position: Chr15, 34.82 cM
• Alliance: Mafa^tm1.1Rwst page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: TL1/TL-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to place two loxP sites in tandem orientation to flank a 2355 bp fragment in the the region beginning 1106 bp upstream of the start codon, including 1081 bp of the coding sequence and ending 171 bp downstream of the stop codon. The vector also contained an FRT-flanked neomycin resistance cassette. The neo cassette was removed by crossing to Tg(ACTFLPe)9205Dym mice. (J:94077)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mafa Mutation: 20 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 11 reference(s)