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Mov10l1tm1.2Jw
Targeted Allele Detail
Nomenclature
Symbol: Mov10l1tm1.2Jw
Name: Moloney leukemia virus 10-like 1; targeted mutation 1.2, Jeremy Wang
MGI ID: MGI:4457276
Gene: Mov10l1  Location: Chr15:88982909-89055148 bp, + strand  Genetic Position: Chr15, 44.49 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:161125
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre mediated recombination removed exons 18 through 21. This allele is predicted to generate a protein lacking most of the ATPase and all of the unwindase domains. The absence of protein expression was confirmed by immunohistochemistry on adult testes. (J:161125)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mov10l1 Mutation:  23 strains or lines available
References
Original:  J:161125 Zheng K, et al., Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway. Proc Natl Acad Sci U S A. 2010 Jun 1;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory