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Targeted Allele Detail
Symbol: Mov10l1tm1.1Eno
Name: Mov10 like RISC complex RNA helicase 1; targeted mutation 1.1, Eric N Olson
MGI ID: MGI:4457212
Synonyms: Mov10l1fl
Gene: Mov10l1  Location: Chr15:88867112-88939355 bp, + strand  Genetic Position: Chr15, 44.49 cM
Germline Transmission:  Earliest citation of germline transmission: J:161124
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA loxP site was inserted upstream of exon 20 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 20. Flp mediated recombination removed the neo cassette leaving exon 20 floxed. (J:161124)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mov10l1 Mutation:  28 strains or lines available
Original:  J:161124 Frost RJ, et al., MOV10L1 is necessary for protection of spermatocytes against retrotransposons by Piwi-interacting RNAs. Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11847-52
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory