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Noxa1tm1.2Brg
Targeted Allele Detail
Nomenclature
Symbol: Noxa1tm1.2Brg
Name: NADPH oxidase activator 1; targeted mutation 1.2, David E Bergstrom
MGI ID: MGI:4457198
Synonyms: Noxa1del1
Gene: Noxa1  Location: Chr2:25085667-25095149 bp, - strand  Genetic Position: Chr2, 16.97 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:164059
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  B6(Cg)-Tyrc-2J/J
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA single loxP site was inserted into intron 2 and an FRT-flanked neomycin/kanamycin selection cassette with a second loxP site was inserted into intron 6. Exons 3 through 6, encoding amino acids 88-220, were excised by cre recombinase mediated excision. This is predicted to result in the incorporation of 19 novel amino acids followed by a premature stop codon. (J:164059)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Noxa1 Mutation:  10 strains or lines available
Notes
ES cell line = PRX-B6-albino #1
References
Original:  J:164059 Flaherty JP, et al., Generation of a conditional null allele of NADPH oxidase activator 1 (NOXA1). Genesis. 2010 Jul 19;:1-8
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory