Kcnh6^{tm1e(EUCOMM)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Kcnh6^{tm1e(EUCOMM)Wtsi}
• Name: potassium voltage-gated channel, subfamily H (eag-related), member 6; targeted mutation 1e, Wellcome Trust Sanger Institute
• MGI ID: MGI:4456840
• Gene: Kcnh6 Location: Chr11:105898950-105925375 bp, + strand Genetic Position: Chr11, 68.87 cM
• IMPC: Kcnh6 gene page

Mutation origin

• Mutant Cell Line: EPD0009_2_A03
• Germline Transmission: Unknown
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion Vector: L1L2_gt0
• Mutation details: The L1L2_gt0 cassette was inserted at position 105909065 of Chromosome 11 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:155845, J:173534)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcnh6 Mutation: 49 strains or lines available

References

• Original: J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010
• All: 2 reference(s)