Jak3tm1(KOMP)Mbp
Targeted Allele Detail
|
Symbol: |
Jak3tm1(KOMP)Mbp |
Name: |
Janus kinase 3; targeted mutation 1, Mouse Biology Program, UC Davis |
MGI ID: |
MGI:4456622 |
Gene: |
Jak3 Location: Chr8:72129027-72143221 bp, + strand Genetic Position: Chr8, 34.43 cM
|
IMPC: |
Jak3 gene page |
|
Mutant Cell Lines: |
DEPD00505_6_A05, DEPD00505_6_A08, DEPD00505_6_B06, DEPD00505_6_C05, DEPD00505_6_C06, DEPD00505_6_D06, DEPD00505_6_D08, DEPD00505_6_E06, DEPD00505_6_E07, DEPD00505_6_F05, DEPD00505_6_H06 |
Germline Transmission: |
Unknown
|
Parent Cell Line: |
JM8A3 (ES Cell)
|
Strain of Origin: |
C57BL/6N-Atm1Brd
|
Project Collection: |
KOMP-CSD
|
|
Allele Type: |
|
Targeted (Null/knockout, Reporter) |
Mutations: |
|
Insertion, Intragenic deletion
Vector: L1L2_Bact_P
|
|
|
Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 1337 starting at position 72131252 and ending at position 72132589 of Chromosome 8 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157064)
|
|
|
|
Original: |
J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010; |
All: |
1 reference(s) |
|