Il21tm1(KOMP)Mbp
Targeted Allele Detail
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Symbol: |
Il21tm1(KOMP)Mbp |
Name: |
interleukin 21; targeted mutation 1, Mouse Biology Program, UC Davis |
MGI ID: |
MGI:4456569 |
Gene: |
Il21 Location: Chr3:37276908-37286785 bp, - strand Genetic Position: Chr3, 18.36 cM, cytoband B
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Alliance: |
Il21tm1(KOMP)Mbp page
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IMPC: |
Il21 gene page |
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Mutant Cell Lines: |
DEPD00507_1_A05, DEPD00507_1_A06, DEPD00507_1_E06, DEPD00507_1_E07, DEPD00507_1_F08, DEPD00507_1_G05, DEPD00507_1_G06, DEPD00507_1_G08 |
Germline Transmission: |
Earliest citation of germline transmission:
J:204812
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Parent Cell Line: |
JM8A3 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 172 starting at position 37286305 and ending at position 37286477 of Chromosome 3 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157064)
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Original: |
J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010; |
All: |
2 reference(s) |
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