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Ube4btm1e(KOMP)Mbp
Targeted Allele Detail
Summary
Symbol: Ube4btm1e(KOMP)Mbp
Name: ubiquitination factor E4B; targeted mutation 1e, Mouse Biology Program, UC Davis
MGI ID: MGI:4455399
Gene: Ube4b  Location: Chr4:149412873-149511206 bp, - strand  Genetic Position: Chr4, 79.08 cM
IMPC: Ube4b gene page
Mutation
origin
Mutant Cell Lines:  DEPD00521_1_A07, DEPD00521_1_B05, DEPD00521_1_B06, DEPD00521_1_B07, DEPD00521_1_C05, DEPD00521_1_C06, DEPD00521_1_C07, DEPD00521_1_D05, DEPD00521_1_D08, DEPD00521_1_E05, DEPD00521_1_E07, DEPD00521_1_F05, DEPD00521_1_F07, DEPD00521_1_G06, DEPD00521_1_G07, DEPD00521_1_G08, DEPD00521_1_H05, DEPD00521_1_H08
Germline Transmission:  Unknown
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_Bact_P
 
Mutation detailsThe L1L2_Bact_P cassette was inserted at position 149472737 of Chromosome 4 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157064)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Ube4b Mutation:  74 strains or lines available
References
Original:  J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory