Chrm1tm1e(KOMP)Mbp
Targeted Allele Detail
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Symbol: |
Chrm1tm1e(KOMP)Mbp |
Name: |
cholinergic receptor, muscarinic 1, CNS; targeted mutation 1e, Mouse Biology Program, UC Davis |
MGI ID: |
MGI:4455370 |
Gene: |
Chrm1 Location: Chr19:8641369-8660970 bp, + strand Genetic Position: Chr19, 5.44 cM
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IMPC: |
Chrm1 gene page |
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Mutant Cell Lines: |
DEPD00521_2_A09, DEPD00521_2_A10, DEPD00521_2_A12, DEPD00521_2_B12, DEPD00521_2_C11, DEPD00521_2_C12, DEPD00521_2_D12, DEPD00521_2_E09, DEPD00521_2_E10, DEPD00521_2_E11, DEPD00521_2_E12, DEPD00521_2_F11, DEPD00521_2_F12, DEPD00521_2_G10, DEPD00521_2_G11, DEPD00521_2_G12, DEPD00521_2_H09, DEPD00521_2_H12 |
Germline Transmission: |
Unknown
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Parent Cell Line: |
JM8 (ES Cell)
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Strain of Origin: |
C57BL/6N
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutation: |
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Insertion
Vector: L1L2_Bact_P
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Mutation details: The L1L2_Bact_P cassette was inserted at position 8654842 of Chromosome 19 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157064)
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Original: |
J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010; |
All: |
1 reference(s) |
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