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Tg(CAG-flpo)1Afst
Transgene Detail
Nomenclature
Symbol: Tg(CAG-flpo)1Afst
Name: transgene insertion 1, A Francis Stewart
MGI ID: MGI:4453967
Synonyms: CAGGs-Flpo, Flpo
Transgene: Tg(CAG-flpo)1Afst  Location: unknown  
Transgene
origin
Germline Transmission:  Earliest citation of germline transmission: J:160215
Parent Cell Line:  JM8.F6 (ES Cell)
Strain of Origin:  C57BL/6N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsA linearized plasmid encoding the CAGGs promoter driving a codon optimized Flp recombinase (Flpo) and an IRES-puromycin sequence was introduced into JM8.F6 ES cells. Two clones were injected into 8-cell C57BL/6 albino embryos. One chimera showed germline transmission when crossed to C57BL/6 albino animals. (J:160215)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: CAG     Summary of all recombinase alleles driven by CAG.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
References
Original:  J:160215 Kranz A, et al., An improved Flp deleter mouse in C57Bl/6 based on Flpo recombinase. Genesis. 2010 Aug;48(8):512-20
All:  42 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory