Mib1^tm2Art
Targeted Allele Detail

Summary

• Symbol: Mib1^tm2Art
• Name: MIB E3 ubiquitin protein ligase 1; targeted mutation 2, Karen Artzt
• MGI ID: MGI:4453843
• Synonyms: mib1-cko
• Gene: Mib1 Location: Chr18:10725548-10818704 bp, + strand Genetic Position: Chr18, 5.35 cM
• Alliance: Mib1^tm2Art page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160208
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting vector contains a loxP-flanked neomycin cassette inserted in intron 2 and a loxP site flanking exon 2. Mice were crossed with mice carrying Tg(EIIa-cre) to remove the neo cassette leaving two loxP sites flanking exon 2. (J:160208)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mib1 Mutation: 55 strains or lines available

References

• Original: J:160208 Artzt K, Creation of conditional Mib1 mutant. MGI Direct Data Submission. 2010
• All: 1 reference(s)