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Tbx1tm3.1Bld
Targeted Allele Detail
Nomenclature
Symbol: Tbx1tm3.1Bld
Name: T-box 1; targeted mutation 3.1, Antonio Baldini
MGI ID: MGI:4453450
Synonyms: Tbx1deltaE5
Gene: Tbx1  Location: Chr16:18581713-18586969 bp, - strand  Genetic Position: Chr16, 11.51 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:91013
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre mediated recombination removed exon 5. The expected product is predicted to cause loss of function with a stop codon after 86 codons. (J:91013)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tbx1 Mutation:  11 strains or lines available
References
Original:  J:91013 Xu H, et al., Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract. Development. 2004 Jul;131(13):3217-27
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory