Nckipsd^tm1.1Toft
Targeted Allele Detail

Summary

• Symbol: Nckipsd^tm1.1Toft
• Name: NCK interacting protein with SH3 domain; targeted mutation 1.1, Tomoko Fukumi-Tominaga
• MGI ID: MGI:4442817
• Synonyms: DIP^flox
• Gene: Nckipsd Location: Chr9:108685567-108696043 bp, + strand Genetic Position: Chr9, 59.63 cM, cytoband F2
• Alliance: Nckipsd^tm1.1Toft page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158332
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted upstream of exon 2 and a loxP site was inserted downstream of exon 5. Cre mediated recombination removed the neo cassette leaving exons 2 through 5 floxed. (J:158332)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nckipsd Mutation: 27 strains or lines available

References

• Original: J:158332 Fukumi-Tominaga T, et al., DIP/WISH-deficient mice reveal Dia- and N-WASP-interacting protein as a regulator of cytoskeletal dynamics in embryonic fibroblasts. Genes Cells. 2009 Oct;14(10):1197-207
• All: 1 reference(s)