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Spontaneous Allele Detail
Symbol: Prkralear
Name: protein kinase, interferon inducible double stranded RNA dependent activator; little ears
MGI ID: MGI:4442387
Gene: Prkra  Location: Chr2:76460242-76478359 bp, - strand  Genetic Position: Chr2, 45.07 cM
Small ears and smaller body size of Prkralear/Prkralear female (left) compared to heterozygote (right) at nine weeks of age

Show the 1 phenotype image(s) involving this allele.

Strain of Origin:  C57BL/6J
Allele Type:    Spontaneous
Mutation:    Single point mutation
Mutation detailsThis spontaneous mutation has a T-to-A transversion at chromosome 2:76,639,197 (GRCm38) in intron 5 immediately adjacent to the conserved splice donor site. (J:176116, J:222308, J:223062)
Inheritance:    Recessive
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Prkra Mutation:  12 strains or lines available
Original:  J:159349 Curtain MM, et al., An Ear Pinna Mutation in the Mouse on Chromosome Two. MGI Direct Data Submission. 2010;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory