A930004D18Rik^{tm1e(EUCOMM)Wtsi}
Targeted Allele Detail

Summary

• Symbol: A930004D18Rik^{tm1e(EUCOMM)Wtsi}
• Name: RIKEN cDNA A930004D18 gene; targeted mutation 1e, Wellcome Trust Sanger Institute
• MGI ID: MGI:4441718
• Gene: A930004D18Rik Location: Chr2:18029998-18042552 bp, - strand Genetic Position: Chr2, 12.82 cM
• IMPC: A930004D18Rik gene page

Mutation origin

• Mutant Cell Lines: EPD0496_3_A03, EPD0496_3_B03, EPD0496_3_C02, EPD0496_3_D03, EPD0496_3_F04, EPD0496_3_G03, EPD0496_3_H02, EPD0496_3_H04
• Germline Transmission: Unknown
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion Vector: L1L2_Pgk_P
• Mutation details: The L1L2_Pgk_P cassette was inserted at position 18033340 of Chromosome 2 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the PGK promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:155845, J:173534)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any A930004D18Rik Mutation: 32 strains or lines available

References

• Original: J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010
• All: 2 reference(s)