Tg(TTR)14Kymm
Transgene Detail

Summary

• Symbol: Tg(TTR)14Kymm
• Name: transgene insertion 14, Ken-ichi Yamamura
• MGI ID: MGI:4441489
• Transgene: Tg(TTR)14Kymm Location: unknown Genetic Position: Chr13, Syntenic
• Alliance: Tg(TTR)14Kymm page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(TTR)14Kymm expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TTR (7276)

  Ttr	(MGI:98865)

• Mutation details: The complete human transthryretin gene was reconstructed using fragments from recombinant plasmids pPATH4 and pPATE1. The gene product has a substitution of methionine for valine at amino acid position 30. The insertion in line 14 appears to contain 6 copies. This line also displays a developmental phenotype. (J:9303, J:92524)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:92524 Yamamura K, et al., Tissue-specific and developmental expression of human transthyretin gene in transgenic mice. Dev Genet. 1987;8(4):195-205
• All: 2 reference(s)