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Smyd2tm1.1Fben
Targeted Allele Detail
Nomenclature
Symbol: Smyd2tm1.1Fben
Name: SET and MYND domain containing 2; targeted mutation 1.1, Felix B Engel
MGI ID: MGI:4441342
Synonyms: Smyd2flox
Gene: Smyd2  Location: Chr1:189880492-189922363 bp, - strand  Genetic Position: Chr1, 95.03 cM, cytoband H6
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:158898
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn frt flanked neo cassette and loxP site were inserted upstream of exon 1 and a second loxP site was inserted downstream of exon 1 vi homologous recombination. The neo cassette was then removed by Flp mediated recombination. (J:158898)
Generation of the Smyd2tm1.1Fben allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 24 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smyd2 Mutation:  132 strains or lines available
References
Original:  J:158898 Diehl F, et al., Cardiac deletion of Smyd2 is dispensable for mouse heart development. PLoS One. 2010;5(3):e9748
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/01/2019
MGI 6.14
The Jackson Laboratory