About   Help   FAQ
Tg(CAG-VCP*R155H)55Jpat
Transgene Detail
Nomenclature
Symbol: Tg(CAG-VCP*R155H)55Jpat
Name: transgene insertion 55, J Paul Taylor
MGI ID: MGI:4440439
Synonyms: VCP-R155H
Transgene: Tg(CAG-VCP*R155H)55Jpat  Location: unknown  
Transgene
origin
Strain of Origin:  SJL
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CAG-VCP*R155H)55Jpat expresses 1 gene
 
Mutation detailsThe CAG promoter was used to drive ubiquitous expression of the human cDNA with nucleotide substitutions resulting in the amino acid substitution of histidine for arginine at position 155 (R155H). Five lines were created with line 55 selected as the representative line. (J:158713)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:158713 Custer SK, et al., Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone. Hum Mol Genet. 2010 May 1;19(9):1741-55
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/07/2015
MGI 5.21
The Jackson Laboratory