Tg(tetO-HTR4*D100A)#Niss
Transgene Detail

Summary

• Symbol: Tg(tetO-HTR4*D100A)#Niss
• Name: transgene insertion #, Robert A Nissenson
• MGI ID: MGI:4438956
• Synonyms: TetO-Rs1
• Transgene: Tg(tetO-HTR4*D100A)#Niss Location: unknown
• Alliance: Tg(tetO-HTR4*D100A)#Niss page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: The transgene vector was constructed to contain an aspartic acid to alanine amino acid residue change at position 100 making the gene product insensitive to serotonin. It is under the control of a TetO promoter. Three lines were established and designated as B (or 2), C, and G (or 7). # denotes the case where no line number is given. (J:131617)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:157921 Hsiao EC, et al., Ligand-mediated activation of an engineered gs g protein-coupled receptor in osteoblasts increases trabecular bone formation. Mol Endocrinol. 2010 Mar;24(3):621-31
• All: 5 reference(s)