Nanog^tm1Hoch
Targeted Allele Detail

Summary

• Symbol: Nanog^tm1Hoch
• Name: Nanog homeobox; targeted mutation 1, Konrad Hochedlinger
• MGI ID: MGI:4438865
• Synonyms: Nanog-GFP
• Gene: Nanog Location: Chr6:122684448-122691592 bp, + strand Genetic Position: Chr6, 57.8 cM, cytoband F2
• Alliance: Nanog^tm1Hoch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158493
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• The coding region was replaced with an GFP-iresPuro cassette. (J:95814, J:158493)

Expression

In Mice Carrying this Mutation:

16 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nanog Mutation: 46 strains or lines available

References

• Original: J:158493 Maherali N, et al., Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell. 2007 Jun 7;1(1):55-70
• All: 10 reference(s)