About   Help   FAQ
Dbn1tm1.1Shira
Targeted Allele Detail
Nomenclature
Symbol: Dbn1tm1.1Shira
Name: drebrin 1; targeted mutation 1.1, Tomoaki Shirao
MGI ID: MGI:4438710
Synonyms: DAKO
Gene: Dbn1  Location: Chr13:55473429-55488111 bp, - strand  Genetic Position: Chr13, 30.06 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:158208
Parent Cell Line:  MS12 (ES Cell)
Strain of Origin:  C57BL/6NSlc
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn FRT-flanked neo cassette was inserted within exon 11a and exon 11a was floxed by homologous recombination. The neo cassette and exon 11a were removed by cre mediated recombination. Western blotting confirmed the presence of the E form instead of the A form in cerebral cortices lysates of adult. (J:158208)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dbn1 Mutation:  26 strains or lines available
References
Original:  J:158208 Kojima N, et al., Genetic disruption of the alternative splicing of drebrin gene impairs context-dependent fear learning in adulthood. Neuroscience. 2010 Jan 13;165(1):138-50
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/19/2016
MGI 6.04
The Jackson Laboratory